PRR5 Antikörper (C-Term)

Produktnummer ABIN6991523

Der Kaninchen Polyklonal Anti-PRR5 Antikörper wurde für WB, ELISA, IF und IHC (p) validiert. Er ist geeignet, PRR5 in Proben von Human, Maus und Ratte zu detektieren.

Kurzübersicht für PRR5 Antikörper (C-Term) (ABIN6991523)

Target: PRR5 (Proline Rich 5 (Renal) (PRR5))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PRR5 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Produktdetails anti-PRR5 Antikörper

Bindungsspezifität: AA 310-360, C-Term

Spezifität: PRR5 antibody is predicted to not cross-react with other Protor protein family members.

Aufreinigung: PRR5 Antibody is affinity chromatography purified via peptide column.

Immunogen: PRR5 antibody was raised against a 20 amino acid synthetic peptide near the carboxy terminus of human PRR5. The immunogen is located within amino acids 310 - 360 of PRR5.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: PRR5 antibody can be used for detection of PRR5 by Western blot at 1 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

Antibody validated: Western Blot in human samples, Immunohistochemistry in mouse samples and Immunofluorescence in mouse samples. All other applications and species not yet tested.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PRR5 Antibody is supplied in PBS containing 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,4 °C

Informationen zur Lagerung: PRR5 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Details zu PRR5

Target: PRR5 (Proline Rich 5 (Renal) (PRR5))

Andere Bezeichnung: PRR5

Hintergrund: PRR5 Antibody: Proline-rich protein 5 (PRR5), also known as Protor-1, is a 388 amino acid protein in Protor family, is thought to act as a tumor suppressor in breast and colorectal tumorigenesis. PRR5 is widely expressed and possesses two RICTOR interaction sites and a C-terminal Proline rich region. It promotes Rapamycin complex 2 (mTORC2) activity. There are four isoforms of PRR5 that are produced as a result of alternative splicing events and these isoforms play an important role in the modulation of platelet-derived growth factor signaling and in the regulation of PDGFR-beta expression.

Gen-ID: 55615

NCBI Accession: NP_851850

UniProt: P85299

Pathways: PI3K-Akt Signalweg